Assisi Animal Health unveils its new line of Calmer Canine® products, which employs a unique tPEMF signal, reducing inflammation in the anxiety center of the brain.

A trial published in the Journal of the American Animal Hospital Association found that using the Assisi Loop to treat dogs with intervertebral disc disease resulted in improved wound healing, a 50% reduction in opioid administration, and zero side effects.14


A clinical trial found that using tPEMF therapy on dogs with spinal injuries resulted in reduced incisional pain, improved neuroprotective qualities, and a statistically greater degree of recovery of proprioception.13


Under new management, Assisi Animal Health increased their focus on validating PEMF technology through clinical research.


FDA approves PEMF therapy for treatment of brain cancer.12


The Assisi LOOP® received its FDA clearance for its PEMF signal that reduces pain and edema.  The science that inspired the Assisi LOOP’s design and treatment regimen is described below.11


Assisi Animal Health is born, founded by incorporating Dr. Pilla’s technology, cleared by the FDA for human medicine, into their portfolio of products for animal health.


FDA approves PEMF therapy for treatment of depression and anxiety.10


FDA approves PEMF therapy for cervical fusion patients at high-risk of non-fusion.9


FDA approves PEMF for urinary incontinence and muscle stimulation7

The Nobel Prize for Medicine and Physiology was awarded to three American pharmacologists: Robert F. Furchgott, Louis J. Ignarro and Ferrid Murad for their work on nitric oxide as a signaling molecule in the cardiovascular system.8


Arthur A. Pilla, PhD develops a relatively low-powered PEMF device – a bone growth stimulator (BGS) – to heal recalcitrant factures.4 (1970)

FDA approves PEMF for the healing of nonunion fractures.5 (1979)

The Assisi LOOP’s patented signal targeting the upregulation of nitric oxide was developed by the late Dr. Arthur Pilla of Columbia University and cleared by the FDA for treating non-healing fractures.6 (1979)


Scientists begin serious research into PEMF therapy as a healing agent.3


Michael Faraday, a British chemist and physicist, discovers electromagnetic induction. The basic law of induction postulated by Faraday is later named “Faraday’s Law,” 1 (1831)

Tesla publishes “The Electrical Engineer” and discusses invention of magnetic loop coil, still used today; led to magnetic strength being measured in Teslas (T).2  (1898)