Calmer Canine® should be used twice a day for 15 minutes each time. Treatments should be spaced 8 to 10 hours apart. Owners simply put the easy to use vest on their dog, attach the device to the neck strap with the Velcro attachment and turn the device on to activate it. The Calmer Canine device will turn itself off after the 15-minute treatment is over. The vest is then removed and set aside until the next treatment.